Novel Monoclonal Antibodies GMab-r1 and LMab-1
Anti-IDH1-R132H (Human) mAb(Monoclonal, HMab-1 from MBL.This clone reacts with mutated IDH1-R132H and does not cross-react with wild type IDH1 and other IDH1 mutants. Application:Western Blotting, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry Reactivity:Human, Hamster, Dog Oct 30, 2015 · Several monoclonal antibodies (mAbs) specific for IDH1 mutations have been established, such as H09, IMab-1, and HMab-1 against IDH1-R132H, which is the most frequent IDH1 mutation in gliomas. In this study, we established a novel high-sensitive mAb HMab-2, which reacts with IDH1-R132H but not with wild type IDH1 in ELISA. More>> Detect Isocitrate Dehydrogenase 1 (IDH1)-R132H using this Anti-Isocitrate Dehydrogenase 1 (IDH1)-R132H Antibody, clone HMab-1 validated for use in Western Blotting, IHC, ICC. Less<< MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Jul 19, 2020 · Bride and Groom sing EPIC Thank You Song to Wedding Guests - Best Wedding speech - Duration: 14:54. Jamie and Megan 3,020,948 views Gliomas constitute approximately 20 percent of brain tumors. Two common types of glioma are astrocytomas and oligodendrogliomas. Isocitrate dehydrogenase 1 (IDH1) R132H mutations occur in approximately 70% of astrocytomas and oligodendroglial tumors.Monoclonal antibody clone H09 is specific for the R132H mutation of IDH1. It does not bind to the unaltered protein. Therefore, if the H09 tissue Sign in to like videos, comment, and subscribe. Sign in. Watch Queue Queue
Jun 09, 2013
For this study, 164 cases of glioma were evaluated immunohistochemically for IDH1 mutations (R132H and R132S) using anti-IDH1 mAbs (HMab-1 and SMab-1). IDH1 mutation was detected, respectively, in 9.7%, 63.6%, 51.7%, and 77.8% of primary grade IV, secondary grade IV, grade III, and grade II gliomas.
July 20, 2020 - YouTube
Mar 15, 2020 · Since the molecular weight of hmAb-1 is almost 10-fold higher than Ag-1, one would expect a larger drop in the binding response following the dissociation of the complex, in comparison to the Ag-1 dissociation. This would reflect a faster apparent dissociation rate in the binding sensorgram, as observed for hmAb-1 and hmAb-3. SAB4200548 Sigma-Aldrich Anti-IDH1 (R132H) antibody, Mouse monoclonal clone HMab-1, purified from hybridoma cell culture Synonym: Anti-NADP(+)-specific ICDH, Anti-IDCD, Anti-IDH, Anti-IDP, Anti-IDPC, Anti-Isocitrate dehydrogenase 1 (NADP+), soluble, Anti-NADP-dependent isocitrate dehydrogenase, cytosolic, Anti-NADP-dependent isocitrate dehydrogenase, peroxisomal, Anti-Oxalosuccinate Jul 19, 2020 · Isocitrate Dehydrogenase 1 (IDH1)-R132H Antibody, clone HMab-1 EMD Millipore catalog: MABC171 total number of products: 4. mouse monoclonal (HMab-1) reactivity: human Anti IDH1-R132H, Monoclonal Antibody (HMab-1) for Immunochemistry: Anti IDH1-R132H, Monoclonal Antibody (HMab-2) for Immunochemistry: Anti IDH1-R132S, Monoclonal Antibody (SMab-1) for Immunochemistry: Anti IDH2, Monoclonal Antibody (RMab-22) for Immunochemistry Clone No.: HMab-1 Host: Mouse Isotype: IgG1 Source: Purified from hybridoma supernatant using protein G agarose Concentration: Indicated on each label Formulation: PBS (pH 7.2) containing 0.05% sodium azide. Applications ELISA: 1 - 5 μg/mL Western Blot: 5 μg/mL Immunohistochemistry: 5 - 10 μg/mL. Note Avoid repeated the freeze and thaw cycle.
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